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Exercise and Cancer: Benefits, Programs, and Prevention

Comprehensive Guide to Exercise and Cancer: Benefits, Programs, and Prevention Strategies

Exercise and cancer: a comprehensive guide

Exercise is increasingly recognized as a critical component of cancer care, offering numerous benefits across all stages of the disease—before, during, and after treatment. Engaging in regular physical activity not only improves overall health but also enhances the quality of life for cancer patients. It can help manage side effects of treatment, reduce the risk of cancer recurrence, and even improve survival rates. This comprehensive guide delves into the role of exercise in cancer prevention, its benefits during treatment, and how it aids in recovery post-surgery.

The role of physical activity in cancer prevention

How Exercise Reduces Cancer Risk

Regular physical activity is one of the most effective lifestyle choices you can make to reduce your risk of developing cancer. Numerous studies have demonstrated that exercise lowers the risk of several common cancers, including breast, prostate, colon, endometrial, and potentially pancreatic cancer. The American Cancer Society's Guidelines on Nutrition and Physical Activity for Cancer Prevention emphasize that higher levels of physical activity are associated with a lower risk of cancer development.
One of the primary ways exercise reduces cancer risk is by helping to regulate hormones, such as estrogen and insulin, that can contribute to the development of cancer. For example, high levels of estrogen are linked to an increased risk of breast cancer, while insulin resistance is associated with several types of cancer, including colon cancer. Regular exercise helps to normalize these hormone levels, thereby reducing cancer risk.


Moreover, exercise strengthens the immune system, enhancing the body’s ability to detect and destroy cancer cells. The immune system plays a crucial role in surveilling the body for abnormal cells, and a stronger immune response can prevent these cells from developing into full-blown cancers.


Another significant benefit of exercise is its role in weight management. Being overweight or obese is a major risk factor for many types of cancer. Excess body fat can produce hormones and growth factors that stimulate cancer cell growth. In the U.S., it is estimated that obesity contributes to approximately 14% to 20% of all cancer deaths. Even modest weight loss can significantly reduce this risk. Exercise helps to maintain a healthy weight, thereby lowering the likelihood of cancer development.

Sedentary Lifestyle and Cancer Risk

In addition to the benefits of exercise, it's important to consider the risks associated with a sedentary lifestyle. Prolonged periods of sitting or inactivity can increase the risk of developing cancer, even in individuals who engage in regular exercise. This is because sitting for long periods is associated with metabolic changes, such as increased insulin levels and chronic inflammation, both of which are risk factors for cancer. A growing body of evidence suggests that reducing sitting time is as important as increasing physical activity when it comes to cancer prevention. Incorporating more movement into your daily routine, such as standing or walking breaks, can help mitigate these risks.

the role of physical activity

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"Don’t buy into that old story that you need to exercise to improve yourself. The truth is you exercise to feel more like yourself: confident and at ease. Besides, it feels good to come home to the body and delight in all the ways it moves! The body is amazing. You are amazing. You and your body make a great team."

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Kathy Therber

Yoga Instructor

Best exercises to support cancer prevention

Aerobic Exercise

Aerobic exercise, also known as cardiovascular exercise, is one of the most effective forms of physical activity for cancer prevention. This type of exercise includes activities like brisk walking, running, cycling, swimming, and even dancing. Aerobic exercise is crucial because it not only improves cardiovascular health and increases lung capacity but also plays a significant role in regulating metabolic processes that are linked to cancer risk. For instance, regular aerobic exercise helps to regulate insulin and hormone levels, both of which, when imbalanced, can contribute to cancer development. Moreover, aerobic exercise reduces chronic inflammation—a known risk factor for various cancers—by lowering levels of inflammatory markers in the body. Additionally, maintaining a healthy weight through consistent aerobic activity is vital, as obesity is a well-documented risk factor for many types of cancer, including breast, colon, and endometrial cancers. Engaging in at least 150 minutes of moderate-intensity aerobic exercise per week, as recommended by health guidelines, can significantly lower the risk of developing cancer.

Strength Training

Strength training, or resistance exercise, involves activities that build muscle mass, increase strength, and improve overall body composition. This can include exercises like weightlifting, resistance band workouts, or bodyweight exercises such as push-ups, squats, and lunges. Strength training is particularly important for cancer prevention because it helps to combat sarcopenia (age-related muscle loss) and osteoporosis (bone density loss), both of which can be exacerbated by cancer treatments. Moreover, maintaining muscle mass through strength training improves metabolic health, which plays a critical role in regulating blood sugar and insulin levels, thereby reducing the risk of cancers associated with insulin resistance, such as colorectal and pancreatic cancers. Incorporating strength training into your exercise routine at least two to three times a week can provide substantial protective benefits against cancer.

Flexibility and Balance Exercises

Flexibility and balance exercises, such as yoga and Pilates, are essential for maintaining joint health, preventing injuries, and enhancing overall physical function. These exercises are particularly beneficial for cancer prevention and recovery because they keep the body limber, reduce stiffness, and improve balance—factors that are crucial for older adults and those recovering from surgery or undergoing treatment. Flexibility exercises help maintain the range of motion in the joints, which can be compromised during prolonged cancer treatments, leading to stiffness and discomfort. Additionally, balance exercises are vital for reducing the risk of falls, which can be particularly dangerous for cancer patients with weakened bones or those taking medications that affect coordination. Regular practice of flexibility and balance exercises not only supports physical health but also enhances mental well-being by promoting relaxation and stress reduction.

Yoga

Yoga is an excellent form of exercise that offers a unique combination of physical, mental, and emotional benefits, making it particularly valuable for cancer prevention and management. Yoga can help manage stress and anxiety, which are common during cancer treatment. It also improves flexibility and reduces fatigue, helping patients maintain their strength and endurance. Restorative yoga, in particular, is a gentle form of yoga that emphasizes deep breathing, relaxation, and gentle stretching. This form of yoga is especially beneficial for cancer patients recovering from surgery or those experiencing the debilitating side effects of chemotherapy. Incorporating yoga into a regular exercise routine can thus be an effective strategy for enhancing overall well-being and reducing cancer risk.

"No matter what level of fitness you have when you are diagnosed with cancer, your fitness level will change as you undergo further testing and treatment. Your body goes through a lot of changes after surgeries and treatments so also listen to your body and be mindful of any aches and pains and don’t start out too hard. Your endurance will not be at the same level but will get there slowly. Be patient with yourself and your body’s current abilities. Your fitness level will improve with time and consistent effort."

Maria Cayelli

Dr. Maria Cayelli

Physician and Cancer Survivor

Exercise during cancer treatment

Mental Health Enhancement

Physical activity is a powerful tool for improving mental health in cancer patients. The emotional toll of a cancer diagnosis and the subsequent treatment process can lead to heightened levels of stress, anxiety, and depression. Regular exercise has been shown to combat these mental health challenges by promoting the release of endorphins, which are natural mood elevators. Exercise also helps reduce levels of cortisol, the body's primary stress hormone, thereby decreasing feelings of anxiety and helping patients cope with their diagnosis. Moreover, physical activity can foster a sense of normalcy and routine, providing patients with a positive focus and a way to regain a sense of control over their lives during a tumultuous time.

Physical Health Benefits

Engaging in regular physical activity during and after cancer treatment is essential for maintaining and enhancing physical health. Exercise helps in preserving muscle mass, improving cardiovascular fitness, and boosting overall endurance, which can be significantly compromised during treatment. Aerobic exercises such as walking, swimming, and cycling are particularly beneficial for maintaining heart health and improving lung capacity. Strength training, even with light weights or resistance bands, helps prevent muscle atrophy and supports joint flexibility. Additionally, regular physical activity aids in managing weight, improving digestion, and enhancing immune function, all of which contribute to better physical outcomes during cancer recovery.

Symptom Control: Managing Fatigue, Anxiety, Depression, and Pain

One of the most challenging aspects of cancer treatment is managing the array of symptoms that accompany it, such as fatigue, anxiety, depression, and pain. Physical activity has been shown to alleviate these symptoms, often more effectively than medication alone. Regular exercise can help reduce cancer-related fatigue by improving energy levels, increasing blood flow, and enhancing sleep quality. It also plays a critical role in managing anxiety and depression, as the endorphins released during exercise have mood-boosting effects that can alleviate feelings of sadness and hopelessness. Furthermore, exercise can help in managing pain by promoting the release of natural pain-relieving chemicals in the body and by improving overall physical resilience.

Boosting Self-Esteem and Quality of Life

Cancer and its treatments can often lead to changes in body image and self-perception, which can negatively impact a patient’s self-esteem. Regular physical activity helps combat these feelings by improving physical appearance through weight management and muscle toning, leading to a better self-image. Beyond the physical changes, exercise also empowers patients by giving them a sense of accomplishment and control over their bodies. This empowerment can translate into improved self-esteem, greater confidence, and an enhanced sense of purpose, all of which contribute to a higher quality of life during and after cancer treatment. Engaging in group exercise activities can also provide social support and a sense of community, further boosting emotional well-being.

Exercise during chemotherapy plays a vital role in maintaining overall health, managing side effects, and improving quality of life. Following the American Cancer Society’s guidelines, it’s recommended that cancer patients and survivors aim for at least 150 minutes of moderate-intensity exercise or 75 minutes of vigorous-intensity exercise each week. This approach not only helps in maintaining a healthy weight but also reduces the risk of cancer recurrence. Here’s a closer look at the types of exercises that are particularly beneficial during chemotherapy:

Walking

Walking is an accessible and effective form of moderate-intensity exercise that can be easily adjusted to match your energy levels. It offers cardiovascular benefits, helping to improve heart health and boost circulation, which is crucial during chemotherapy. Whether it’s a leisurely stroll around your neighborhood or a more brisk walk, this activity helps maintain mobility and can be done in short intervals throughout the day. It also provides an opportunity to get outdoors, which can positively impact mood and mental health.

Resistance training (strength training)

Incorporating strength training exercises at least two days per week is crucial for maintaining muscle mass and bone density, both of which can be compromised during chemotherapy. Light resistance training, using resistance bands, light dumbbells, or even body weight exercises, helps combat muscle wasting, a common side effect of cancer treatment. These exercises should be performed with proper form and under the guidance of a healthcare professional to avoid injury.

Swimming

Swimming is another excellent choice for those undergoing chemotherapy. Swimming provides a full-body workout that engages multiple muscle groups, enhances cardiovascular health, and improves endurance. The soothing nature of water can also help alleviate stress and provide a sense of calm. Even if swimming isn’t feasible, simply being in the water, such as walking or doing gentle exercises in a pool, can be beneficial.

Yoga

Yoga, particularly gentle or restorative styles, is highly recommended for cancer patients. It combines physical postures with deep breathing and meditation, making it a holistic exercise that addresses both the body and mind. Yoga helps improve flexibility, balance, and muscle strength while reducing stress and anxiety. Mindfulness practices, such as meditation or guided relaxation, can be incorporated into yoga sessions or practiced separately to manage pain, enhance mental clarity, and promote relaxation. These practices are especially useful during the often physically and emotionally demanding chemotherapy process.

Stretching

Stretching exercises are essential for improving flexibility and preventing injuries. They help maintain joint range of motion and can alleviate stiffness that might result from prolonged periods of inactivity or the effects of chemotherapy. Incorporating a regular stretching routine, ideally daily, can enhance your overall mobility and reduce the risk of muscle strains. Stretching also complements other forms of exercise, such as walking or strength training, by preparing the muscles for activity and aiding in recovery afterward.

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Exercise programs for cancer patients and survivors

Cancer Exercise Programs

The American Cancer Society provides specific guidelines for physical activity for cancer patients and survivors. These guidelines recommend at least 150 minutes of moderate-intensity exercise or 75 minutes of vigorous-intensity exercise each week. The goal is to improve overall fitness, maintain a healthy weight, and reduce the risk of cancer recurrence.

The American Cancer Society’s Guidelines for Cancer Survivors

For cancer survivors, the guidelines emphasize the importance of avoiding inactivity and returning to normal activities as soon as possible. It’s crucial to gradually increase the amount and intensity of exercise, especially for those who were not physically active before their diagnosis. The guidelines recommend:

  • Engaging in 150-300 minutes of moderate-intensity or 75-150 minutes of vigorous-intensity activity each week.

  • Incorporating strength training exercises at least two days per week to maintain muscle mass and bone density.

  • Including stretching exercises to improve flexibility and prevent injuries.

Tailored Exercise Routines

For patients undergoing chemotherapy or radiation therapy, exercise routines should be tailored to individual needs and capabilities. Light activities such as walking, yoga, or gentle stretching can be beneficial during treatment. As the patient’s strength and energy levels improve, the intensity and duration of exercise can be gradually increased.

Special Considerations for Different Types of Cancer

Different types of cancer and their treatments can affect the body in unique ways, necessitating specific exercise approaches. For example, prostate cancer patients undergoing androgen deprivation therapy may experience muscle loss and weight gain, making strength training particularly important. Similarly, patients with lung cancer may benefit from exercises that improve lung capacity and overall cardiovascular health.

The science behind exercise and cancer

Physical exercise has been shown to influence tumor growth and progression through various biological mechanisms. Exercise can induce metabolic changes in the body and within tumors, affecting cancer cell metabolism and potentially slowing tumor progression. These effects are thought to be mediated by several factors, including changes in hormone levels, improved immune function, and reduced inflammation.

Hormonal Changes

Exercise helps regulate hormones like insulin, estrogen, and growth factors, which are involved in the development and progression of certain cancers. For example, regular physical activity lowers insulin levels, reducing the risk of insulin resistance—a condition linked to cancer development. Similarly, exercise can help lower circulating levels of estrogen, reducing the risk of hormone-dependent cancers such as breast and endometrial cancer.

Immune System Enhancement

Regular exercise has been shown to enhance immune function, increasing the body’s ability to detect and destroy cancer cells. Exercise stimulates the production of natural killer cells, a type of white blood cell that plays a crucial role in the immune system’s ability to target and eliminate cancer cells. A study published in Cancer Immunology Research found that regular exercise increased the activity of these cells, leading to slower tumor growth in animal models.

Inflammation Reduction

Chronic inflammation is a known risk factor for cancer. Exercise has anti-inflammatory effects, reducing the levels of inflammatory markers in the body. By lowering inflammation, exercise helps create a less favorable environment for cancer cells to grow and spread. A study published in the Journal of Clinical Oncology found that cancer patients who engaged in regular physical activity had lower levels of C-reactive protein (CRP), a marker of inflammation, compared to inactive patients.

Exercise Oncology: A Growing Field

Exercise oncology is an emerging field that focuses on the role of physical activity in cancer prevention, treatment, and recovery. This field is gaining recognition as more research demonstrates the profound impact of exercise on cancer outcomes. The American College of Sports Medicine has developed guidelines for exercise in cancer patients and survivors, emphasizing the importance of integrating physical activity into cancer care plans.

Tailored Exercise Programs

The development of tailored exercise programs for cancer patients is a key focus of exercise oncology. These programs take into account the type and stage of cancer, the treatments being received, and the patient’s overall health and fitness level. By customizing exercise routines, healthcare providers can help patients achieve the maximum benefit from physical activity while minimizing the risk of injury or adverse effects.

"Part of living an anticancer lifestyle includes exercise. Now exercise can be hard as a cancer survivor. You may be at a point in your journey where you just barely have the energy to get through the day to day, or take care of your personal needs, and exercise seems truly monumental. Or your life is filled and busy with work, family, to-do lists, and you don’t think you can fit it in the time for exercise. But what about a simple walk? Walking is exercise right?"

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Donna McMillan

Ovarian Cancer Survivor

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FAQs about exercise and cancer

Exercise plays a vital role in cancer prevention, treatment, and recovery. Regular physical activity can significantly reduce the risk of developing certain cancers, improve outcomes during treatment, and enhance the quality of life for survivors. By integrating tailored exercise programs into cancer care, patients can improve their physical and emotional well-being, manage side effects, and potentially increase their chances of survival. As always, it is essential to consult with healthcare professionals to create an exercise plan that meets your specific needs and conditions

Can exercise help prevent cancer?

Answer: Yes, regular physical activity has been shown to reduce the risk of several types of cancer, including breast, colon, and endometrial cancer. Exercise helps prevent cancer by improving immune function, reducing inflammation, regulating hormones like estrogen and insulin, and helping maintain a healthy weight.

What are the best exercises during chemotherapy?

Answer: Low-impact exercises such as walking, swimming, and gentle yoga are often recommended during chemotherapy. These activities help manage fatigue, maintain muscle strength, and improve overall well-being without overtaxing the body. It's important to tailor your exercise routine to your energy levels and consult with your healthcare provider.

How soon after surgery can I start exercising?

Answer: It's important to consult with your healthcare provider before starting any exercise after surgery. Generally, gentle exercises, such as stretching or light walking, can be started a few days to weeks after surgery, depending on your recovery progress and the type of surgery you underwent. Exercises focusing on restoring mobility and preventing stiffness, especially after surgeries like mastectomy, can be particularly beneficial.

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